|
KMID : 0357520130360030227
|
|
Journal of Radiological Science and Technology
2013 Volume.36 No. 3 p.227 ~ p.235
|
|
|
The Evaluation of Composite Dose using Deformable Image Registration in Adaptive Radiotherapy for Head and Neck Cancer
|
|
Hwang Chul-Hwan
Ko Seong-Jin
Kim Chang-Soo
Kim Jung-Hoon
Kim Dong-Hyun
Choi Seok-Yoon
Ye Soo-Young
Kang Se-Sik
|
|
|
Abstract
|
|
|
|
In adaptive radiotherapy(ART), generated composite dose of surrounding normal tissue on overall treatment course which is using deformable image registration from multistage images. Also, compared with doses summed by each treatment plan and clinical significance is considered. From the first of May, 2011 to the last of July, 2012. Patients who were given treatment and had the head and neck cancer with 3-dimension conformal radiotherapy or intensity modulated radiotherapy, those who were carried out adaptive radiotherapy cause of tumor shrinkage and weight loss. Generated composite dose of surrounding normal tissue using deformable image registration was been possible, statistically significant difference was showed to mandible($48.95{pm}3.89$ 수식 이미지 vs $49.10{pm}3.55$ 수식 이미지 Gy), oral cavity($36.93{pm}4.03$ 수식 이미지 vs $38.97{pm}5.08$ 수식 이미지 Gy), parotid gland($35.71{pm}6.22$ 수식 이미지 vs $36.12{pm}6.70$ 수식 이미지 Gy) and temporomandibular joint($18.41{pm}9.60$ 수식 이미지 vs $20.13{pm}10.42$ 수식 이미지 Gy) compared with doses summed by each treatment plan. The results of this study show significant difference between composite dose by deformable image registration and doses summed by each treatment plan, composite dose by deformable image registration may generate more exact evaluation to surrounding normal tissue in adaptive radiotherapy.
|
|
|
KEYWORD
|
|
|
Adaptive Radiotherapy (ART), Deformable Image Registration, Dose Volume Histogram (DVH)
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|